This has some effect on reducing the fluid in the circulation, which reduces blood pressure. 'Water' tablets (diuretics) work by increasing the amount of salt and fluid that you pass out in your urine. Calcium-channel blockers can also be used to treat angina.įor more information see the separate leaflet called Calcium-channel Blockers.
This has a relaxing effect on the blood vessels. So, they have a similar effect to ACE inhibitors (described above) and you will need blood tests at the same times as your would if you were taking ACE inhibitors.Ĭalcium-channel blockers affect the way calcium is used in the blood vessels and heart muscle. They work by blocking the effect of angiotensin II on the blood vessel walls. The ones available in the UK are: azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan and valsartan. These medicines are sometimes called angiotensin-II receptor antagonists. Then, a yearly blood test is usual.įor more information see the separate leaflet called ACE Inhibitors. The blood test is repeated within two weeks after starting the medicine and within two weeks after any increase in dose. This will check that your kidneys are working well. You will need a blood test before starting an ACE inhibitor. ACE inhibitors are not used in pregnant or breastfeeding women. They are often used for people with chronic kidney disease. If there is less of this chemical, the blood vessels relax and widen and so the pressure of blood within the blood vessels is reduced.Īn ACE inhibitor is particularly useful if you also have heart failure or diabetes. This chemical tends to narrow (constrict) blood vessels. Angiotensin-converting enzyme (ACE) inhibitorsĪCE inhibitors work by reducing the amount of a chemical, called angiotensin II, that you make in your bloodstream.
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